Langer-Giedion syndrome is a very rare genetic disorder that occurs when a chrosomal material is deleted. This syndrome is also known as trichorhinophalangeal syndrome or LGCR (for Langer-Giedion Chromosome Region). This medical condition is named after the two doctors dig into research about this condition during the 1960s.

Diagnosis is achieved immediately at birth or in early childhood years.

Symptomatic treatment is the present approach to Langer-Giedion Syndrome because it is a genetic disorder; there is no available treatment to completely cure the syndrome. Present medical practice utilizes the importance of external fixators designed for limbic and facial reconstruction.

The signs and symptoms of Langer-Giedion syndrome include the following: * Short stature * Unique facial features * Mild to moderate learning difficulties * Small head * Bony growths usually visible from the bone surfaces * Fine scalp hair * Large ears * Bulbous nose * Deep-set eyes * Missing teeth * Elongated and narrow nose * High and broad eyebrows

Langer-Giedion syndrome is caused by a missing chromosomal material; specifically a tiny piece of chromosome 8’s long arm. This piece carries a number of genes. Losing these genes is the causative factor for all the symptoms of Langer-Giedion syndrome.