Definition:
Diabetes Insipidus is a medical condition referring to inability of the kidney to concentrate urine; characterized by excretion of large amounts of severely diluted urine that cannot be trimmed down even if you reduce the amount of fluid intake.
Diagnosis:
Diagnostic procedures necessary to confirm diagnosis of Nephrogenic Diabetes Insipidus and all types of Diabetes Insipidus are the following:
* Urinalysis
Treatment:
Nephrogenic diabetes Insipidus can be improved through administration of the diuretic hydrochlorothiazide, which is diuretic drug effective in inhibiting the kidney's ability to retain fluid. In addition to this generic drug, amiloride, which is a potassium sparring diuretic is combined for the purpose of preventing the occurrence of hypokalemia.
Indomethacin can also improve the condition of persons with Diabetes Insipidus. Treatment using any of these medications should be combined with adequate rehydration because patients with Diabetes Insipidus are prone to dehydration.
Symptoms and Signs:
Persons with Diabetes Insipidus present the following signs and symptoms:
* Too much urination
* Intense thirst
* Eating too much
* Signs of dehydration
* Unexplainable weight gain
* Appetite interruption
* Delayed growth
* Fever
* Vomiting
* Diarrhea
Causes:
Diabetes Insipidus is caused by lack of Antidiuretic hormone (known as vasopressin) or by the kidney's insensitivity to that hormone.
Diabetes Insipidus can also be generated by the administration of the diuretic conivaptan, which is a non-peptide inhibitor of Antidiuretic hormone (vasopressin).
:
nephrogenicdiabetesinsipidus
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