Definition:
Nephrosclerosis is a medical condition referred to as hypertensive nephropathy, which is a medical condition indicating damage to the kidney because of chronic high blood pressure.
Nephrosclerosis is characterized by hardening of the kidney's artery and arterioles.
Symptoms and Signs:
Nephrosclerosis can sometimes be asymptomatic or incapable of showing any sign of presence of the disease. Though at times, recurrent and chronic hypertension is an indication of that nephrosclerosis is slowing invading the kidney.
Causes:
Due to chronic hypertension, hyaline begins to accumulate in the small arteries and arteriole's wall; due to thi accumulation the walls will then begin to thicken and lumen (opening) starts to narrow. This condition is referred to as hyaline arteriosclerosis. This will result to restricted blood supply (ischemia) producing interstitial fibrosis, tubular atrophy, glomerular alterations and periglomerular fibrosis. The nephrons would then become tightened and shrink in size becomes of ischemia.
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