Definition:
Mixed gonadal dysgenesis is a condition of unusual and asymmetrical gonadal development leasing to an unassigned sex differentiation. Considering that the gonads in this medical condition may not be symmetrical, the development of the Mullerian and Wolffian duct may asymmetrical too (Donahoe PK, Crawford JD, Hendren WH Mixed gonadal dysgenesis, pathogenesis, and management. Pediatr Surg. 1979 Jun;14(3):287-300).
Diagnosis:
Diagnosis includesthe histological examinations of the gonads and thorough examination of the resected or biopsied gonadal tissue.
Treatment:
Treatments includes hormonal treatment after reaching puberal age.
Symptoms and Signs:
Symptoms includes penoscrotal hypospadias, partially formed uterus, presence of fallopian tubes in the male sexes, enlarged clitoris, hypospadias, gonad abnormalities and varying degree of virilization.
Causes:
It is usually caused by the abnormality with the gonads and sex chromosomes.
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