Goodpasture Pneumorenal Syndrome
Definition:

Goodpasture pneumorenal syndrome, otherwise known as Goodpasture's disease and anti -glomerular basement membrane disease is a condition wherein there is rapid destruction of the kidneys and hemorrhaging of the lungs.


Diagnosis:

Diagnosis of the Goodpasture's syndrome includes blood test and biopsy of the kidneys and the lunds (National Kidney and Urologic Diseases Information Clearinghouse, April 2007, pp. 2-4)


Treatment:

It is commonly treated with oral immunosuppressive drugs like cyclophosphamide and corticosteroids.


Symptoms and Signs:

Symptoms vary depending on whether the patient's lung and kidney are affected. In case the lungs are affected, the symptoms include serious and more often dry cough and breathlessness. In cases where the patient's kidney is affected the common symptoms include blood leaks in the urine, loss of appetite, high blood pressure and edema or the swelling caused by fluid retention.


Causes:

Cause of the syndrome is linked to gene inheritance, exposure to certain chemicals like hydrocarbon solvents and weed killer paraquat and other viral infections.


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goodpasturepneumorenalsyndrome



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