Definition:
It is a an angiocentric and angiodestructive lymphoreticular proliferative disorder which commonly affects the lungs, skin and the central nervous system.
Diagnosis:
Biopsy of the lymph nodes, historical evaluation of tonsils, bone marrow, liver, bowel and skin are the most common way of diagnosing the disease. Other test includes bone and chest x-rays , lymphangiography, liver and spleen scan.
Treatment:
There is currently no cure to this disease but there is a protocol being run by Dr. Wyndham H. Wilson at the NIH which has had extraordinary results in which a significant percentage of participants see extended remission periods. The experimental treatment involves the use of interferons to re-set the immune system (National Cancer Institute: Clinical Trials at NIH: Clinical Research: Clinical Trial Spotlight: Lymphomatoid Granulomatosis NCI-94-C-0074).
Symptoms and Signs:
Common symptoms include cough and dyspnea, sputum production, fever, weight loss and malaise. Erythematous macules, papules also shows and extensive lymphocytic infiltration of meninges also are found to patients.
Causes:
The cause of Lymphomatoid granulomatosis is unknown however there are some theories that points to viral sources.
:
lymphomatoidgranulomatosis
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