Definition:
Lysosomal disorder is among the group of forty human genetic disorders that results from malfunction of the lysosomal (Winchester B, Vellodi A, Young E (2000). "The molecular basis of lysosomal storage diseases and their treatment". Biochem. Soc. Trans. 28 (2): 150–4).
Diagnosis:
Diagnosis includes urine screening test, lysosomal enzyme screening test and other hispathological techniques are used to detect the disease.
Treatment:
Bone marrow transplant and enzyme replacement therapies including gene therapies are possible treatment for the disease (Ponder KP, Haskins ME (2007). "Gene therapy for mucopolysaccharidosis". Expert Opin Biol Ther 7 (9): 1333–45).
Symptoms and Signs:
Symptoms include regression of learned skills, onset of dementia, loss of motor control and organ enlargement.
Causes:
One of the known causes of Lysosomal disorder is the defect on the lysosomal metabolism of a person.
