Definition:
Macroglossia dominant refers to the severe enlargement or hypertrophy of the tongue which cause functional difficulties in speaking, eating, and sleeping. It is most common in primary and myeloma-related amyloidosis, which refers to the accumulation of insoluble proteins in tissues that impedes its normal functioning (Merck Manual 17th Ed.)
Diagnosis:
Examination of the family history and physical examination of the tongue are used to diagnose the presence or absence of Macroglossia dominant.
Treatment:
Surgery is the most common treatment for the enlargement of the tongue.
Symptoms and Signs:
Severe enlargement of the tongue is the symptom of the disease.
Causes:
Macroglossia is caused by idiopathic muscle hypertrophy, gland hyperplasia and hemangioma. It may also be caused by hypothyroidism, cretinism and diabetes
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