Definition:
SAPHO syndrome encompasses a range of chronic inflammatory bone diseases usually associated with skin changes.
Treatment:
SAPHO syndrome patients are treated based on clinical symptoms. Commonly, therapy is focused on reducing the inflammation in affected tissues. Non-steroidal anti-inflammatory drugs and corticosteroid medications are prescribed. In addition, topical cold applications can also help reduce symptoms.
Symptoms and Signs:
In general, SAPHO syndrome disorders share common radiologic, clinical, and pathologic characteristics, all involving the bone, skin, and joints.
Classic presentations of SAPHO syndrome can be summarized by its eponym, meaning: Synovitis (or inflammation of the joint lining), Acne (usually in the face and upper back), Pustulosis (inflammatory skin condition), Hyperostosis (abnormal excessive growth of bone), and Osteitis (bone inflammation).
