Thrombocytopathy
Definition:

Thrombocytopathy is any of several blood disorders characterized by dysfunctional platelets (thrombocytes), which leads to prolonged bleeding time, defective clot formation, and a tendency to hemorrhage.


Treatment:

Treatment depends on the underlying disease.


Symptoms and Signs:

Symptoms of thrombocytopahy include: abnormal blood clotting, prolonged bleeding time, hemorrhage, excessive bleeding, abnormal blood platelet function, excessive menstrual bleeding, bleeding gums, gastrointestinal bleeding, blood in urine and stool, bleeding nose, easy bruising, bleeding into the skin, and excessive bleeding following injury and surgery.


Causes:

This arises from a deficiency of the glycoprotein IIb/IIIa complex. Platelets are not able to aggregate. The more severe type I arises from a complete absence of the glycoprotein IIb/IIIa complex, while in the milder type II, some of the glycoprotein IIb/IIIa complex is retained.