Urogenital adysplasia syndrome or renal agenesis is a rare disorder characterized by anomalies of the kidneys, urinary tract, and/or reproductive system.

The signs and symptoms of urogenital adysplasia syndrome vary from individual to individual but most people diagnosed with urogenital adysplasia syndrome have anomalies in their urinary and reproductive tract. Missing kidneys and uterine abnormalities are the most common findings. There are specific features however namely one or two missing kidneys, one or two malformed kidneys, bladder anomalies, hypertension, vaginal anomalies, uterine anomalies, fallopian tube anomalies, lack of menstrual period, and cyst of the seminal vesicle. ------------------------------------------------------------------------------------------------------------Causes The disease is an autosomal dominant inherited condition and is referred to as hereditary renal adysplasia (HRA), renal agenesis, and bilateral agenesis (BRA). ----------------------------------------------------------------------------------------------------------------------Treatment The disease has no specific treatment that can remove, cure, or fix its underlying genetic error. Treatment therefore is limited to the management of specific symptoms. For those with only one kidney, a nephrologist should evaluate their need for antihypertensive agents and/or kidney transplant. ----------------------------------------------------------------------------------------------------------------------Diagnosis A physical examination by a medical geneticist or other physician aid in the diagnosis of Urogenital adysplasia. Parents and siblings of infants born with the disease may undergo ultrasonographic screening since the diagnosis can have implications for their health and medical care.

urogenitaladysplasia