Definition:
Wallis Zieff Goldblatt syndrome otherwise known as the cleidorhizomelic syndrome is a medical condition which can be described as an inherited skeletal disorders which is manifest mainly through the rhizomelic short stature and defects in the lateral clavicular of the person affected (Wallis C, Zieff S, Goldblatt J (1988). "Newly recognized autosomal dominant syndrome of rhizomelic shortness with clavicular defect". Am J Med Genet 31 (4): 881-5).
Diagnosis:
Diagnosis includes the physical examination of the person and the examination of the person's family history. To confirm the presence of the medical condition, diagnosis will often includes the use of radiographs of the lateral third of the clavicles which may be marked by bilateral clinodactyly of the fifth fingers which is usually associated with the hypoplastic middle phalanx.
Treatment:
A t present there is no known treatment yet for the Wallis Zief Goldblatt Syndrome.
Symptoms and Signs:
Person with Wallis Zief Goldblatt Syndrome usually presents rhizometic shortening most especially in the arms and protuberance over the lateral aspects of the clavicles. Bifid appearance of the clavicles resulting from the abnormal process or protuberance are also noted. Thus, person affected with this syndrome usually has short stature.
Causes:
Wallis Zieff Goldblatt syndrome is an inherited disorder which has an autosomal dominant pattern of inheritance.
