Definition:
Wilms' tumor otherwise known as the nephroblastoma, is a tumor which often leads to cancer of the kidneys that more frequently occurs in children. It is frequently detected to children between the ages of two and three and often manifests as a lump in the abdomen.
Diagnosis:
Diagnosis often includes undergoing a computed tomography or CT-Scan which examines the chest area and pelvis for any signs of the tumor.
Treatment:
Treatment usually depends on the stage of the Willm's tumor. It usually includes chemotherapy, radiation. Biologic therapy or combination of both.
Symptoms and Signs:
Symptoms often includes a lump in the abdomen and blood in the urine. There is also a mutation on the 11th chromosome (Call K, Glaser T, Ito C, Buckler A, Pelletier J, Haber D, Rose E, Kral A, Yeger H, Lewis W (1990). "Isolation and characterization of a zinc finger polypeptide gene at the human chromosome 11 Wilms' tumor locus". Cell 60 (3): 509-20).
Causes:
Usually Willm's tumor is linked or said to be cause by genetic conditions and is often said to be inherited while some theory says that it is caused by defects in birth.
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