Definition:
Bare lymphocyte syndrome is a hereditary immunodeficiency disorder distinguished by T- and B-cell dysfunction and these cells are important in aiding to fight the infection. The group of genes is referred as major histocompatibility compound class II or MHC class II is not articulated. The absence of treatment can cause death in infants because of infection.
Treatment:
Bone marrow transplant is the recently known treatment though BLSII is a possible candidate for gene therapy.
Symptoms and Signs:
The list below is the known symptoms of Bare lymphocyte syndrome:
Persistent diarrhea
Malabsorption
Mucocutaneous candidiasis
Upper respiratory tract bacterial infection
Lower respiratory tract bacterial infection
Failure to thrive
Fatigue
Take note that not all the symptoms is evident to the patient other symptoms can be determined by a physician only.
Complications:
The main result bare lymphocyte syndrome is that it severely compromises the immune system and cannot efficiently fight infection. Medically it is known as a severe combined immunodeficiency (SCID).
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