Definition:
Thiamin Deficiency otherwise known as Beriberi, is a medical condition that refers to the lack of thiamine pyrophospate, which is the active form of vitamin known as Vitamin B-1, which acts as a coenzyme in carbohydrate metabolism and the formation of glucose.
Diagnosis:
Diagnosis is made through undergoing laboratory examination to confirm blood thiamine and alpha-ketoglutarate, measuring urinary methylglyoxal and serum thyroid stimulating hormone.
Treatment:
Treatment includes prompt administration of parenteral thiamine and undergoing therapy as well as taking thiamine rich diet which may include vegetables, grains, shrimp and mussles.
Symptoms and Signs:
Symptoms includes fatigue, poor memory, irritability, sleep disturbance, muscle cramps, decreased or reduced vibratory position sensation, muscle atrophy, ankle jerking, chest pain, heart failure,constipation, aphnonia, congestive heart failure, abdominal discomfort, sudden weight loss and weakness.
Causes:
It is said to be caused by not taking enough vitamin B-1 or through taking too much food that are anti-thiamine such as tea, coffee, and may be caused also by folate deficiency.
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