Definition:
Russell-Silver syndrome is a rare disorder that affects slow development, low birth weight, and obvious differences in the size of the sides of the body.
Diagnosis:
The disease can be diagnosed by blood sugar tests, growth hormone studies, chromosome testing and skeletal surveys.
Treatment:
The disease can be treated with proper intake of growth hormones as well as undergoing physical therapy.
Symptoms and Signs:
Among the symptoms present in a person with the disorder is the ability to thrive, slow growth, short stature, short, stubby fingers, and kidney problems.
Causes:
The main cause of the disorder is the defect in the persons’ chromosome 7, wherein the gene is afflicted with maternal uniparental disomy. Other causes of the illness are brought by chromosome translocations and abnormal methylation of chromosome 11p15.
