Definition:
Dermatopathia pigmentosa reticularis is a congenital disorder most common in women. It is a rare type ectodermal dysplasia disorder. Although most cases are reported in Europe, there is not enough evidence to say that the disease is associated with any race.
Diagnosis:
For this disease, findings of a cutaneous biopsy may be helpful in the diagnosis as well as the punch biopsy of the pigmentation in the reticular area.
Treatment:
There is no specific medical care for this disease, however symptomatic management of some of the conditions being associated to this disorder like palmoplantar hyperkerastosis are being administered. For such method, the use of keratolytics and topical retinoic acids could be of great help while cold compress can be very helpful too.
Symptoms and Signs:
Patients with this disease manifest symptom s like lack or absence of dermatoglyphics, heat intolerance, hypohidrosis, nail dystrophy, diffuse alopecia, and enamel defects.
Causes:
This disease is caused by a dominant mutations in keratin 14 protein which is responsible for the healthy formation and development of our hair and skin. It is also suggested that the disease is hereditary in nature, a genetic disorder which is inherited in an autosomal dominant fashion.
