Definition:
Acute intermittent porphyria is a very rare metabolic disorder that is characterized by an abnormal deficiency of porphobilinogen deaminase enzyme that would result to the buildup of polyphyrins. This medical condition is inherited and is passed on from one generation to another.
Diagnosis:
To properly diagnose this disease, several laboratory tests on the patient's urine sample needs to be performed to determine any increase of the heme precursors. Relative of the patient who does not display any symptom can still be identified as carriers through the measurement of the red blood cells and undergoing DNA testing.
Treatment:
Attacks of acute intermittent porphyria can be best deflected through the diligent maintenance of the patient's nutrition as well as the avoidance of medications that may trigger the disorder. Heme is also administered to prevent any attacks.
Symptoms and Signs:
For patients who inherited and are suffering from AIP, most symptoms usually manifest right after puberty, especially among women who undergo hormonal influences. These symptoms occur as attacks that can go on for hours and possibly stretch for several days. Indicators include severe abdominal pain, vomiting, constipation nausea, urinary retention, palpitation, seizures and hallucinations. Patient may also feel pain around the arms, legs and beck area and well as general muscle weakness.
Causes:
Acute intermittent porphyria is acquired through the genes. Studies have shown that this medical condition is remarkably more prevalent in Northern Europe and are known to be more common among women.
:
acuteintermittentporphyria
The information on this site is for research purposes only and can not substitute for the advice of a medical professional. Ailments.com is not run by doctors and does not engage in the practice of medicine. Our site is not a medical authority, it is just a research tool for you to use in preparation for consulting with a doctor. We can not guarantee our information is accurate or up to date. Even if a statement made about a medical condition is accurate, it may not apply to you or your symptoms, so you should always consult a doctor. Nothing on our site should be construed as an attempt to offer or render a medical opinion or otherwise engage in the practice of medicine.
