Definition:
Factor X Deficiency, Congenital -is an uncommon inherited disorder that involves the lack of a protein, known as Factor X, in one’s blood. The deficiency in the protein leads to blood clotting problems, ranging from mild to serious. Women affected by the deficiency may experience extremely heavy menstrual flow, as well bleeding following delivery.
Diagnosis:
Diagnosis is based on medical history, physical examination, laboratory diagnosis, and tests.
Treatment:
This bleeding disorder is treated by getting fresh frozen plasma into one’s blood during acute or sudden episodes, or prior to surgery. If the cause of the disorder is amyloidosis, surgery is performed to remove one’s spleen.
Symptoms and Signs:
Some of the common symptoms of the disorder include nosebleeds, muscle bleeding, bleeding of the mucous membrane, prolonged bleeding, thromboembolism, easy bruising, spontaneous bleeding of the tissue, and blood loss into joints. There are cases of complications, where sudden blood loss or hemorrhage can occur. The joints can get malformed in severe types due to many bleeds.
Causes:
The deficiency is caused by a defective Factor X gene, passed on through families. Another cause is amyloidosis, which is a disorder wherein protein fibers can’t dissolve tissue and organ deposits that affect its function.
