Definition:
Fibrosarcoma is characterized as a tumor of the mesenchymal cell origin that is primarily composed of several malignant fibroblasts in collagen background. It typically occurs as a soft-tissue mass or a bone tumor. There are generally two main types of fibroscarcoma: primary and seconday. The former involves a fibroplastic malignancy producing varying amounts of collagen. Secondary fibrosarcoma results from a preexisting lesion.
Diagnosis:
The diagnosis for fibrosarcoma includes plain radiographs to evaluate the primary or secondary bone involvement. CT scans and MRI are also conducted to detect signs of fractures and check the size of the lesion as well as its involvement in the neurovascular structures. Bone scans and biopsy also assist in the diagnosis.
Treatment:
Treatments for fibrosarcoma include radiation as well as chemotherapy, which are known to considerably improve local control. Surgical procedure may also be performed in some cases.
Symptoms and Signs:
Fibrosarcomas usually involve pain and swelling, and can develop into large mass that can threaten the structural integrity of the bone. Lesions are also key indicators usually occur on the patient's knee, hip and femur regions or in the proximal arm.
Causes:
The underlying cause of fibrosarcoma is still largely unknown, although it is believed that genetic mutation may have played a significant role. It has also been noted that fibrosarcoma may arise from preexisting lesions.
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