Bovine popular stomatitis is a condition that occurs in cattle from all parts of the world. This condition usually occurs during the first two years of the animal’s life. Re-infection is possible due to the short immunity duration. Some handlers are also infected with this condition, which results in lesions on their hands.

Differential diagnosis is important to check for foot-and-mouth disease as they show similar symptoms.

Symptoms of bovine popular stomatitis include reddish and raised lesions on the muzzle, mouth and lips. These lesions are sometimes ulcerative.

This disease is caused by a virus from the Poxviridae family and Parapoxvirus genus.